Zinc (Zn) is one of the trace minerals which is required for huge range of bodily functions. Since last two decades, Zn as micronutrient is being used indiscriminately in agricultural and husbandry practices and also in baby foods and multivitamin supplements since Zn is non-toxic and promotes body weight in the consumers. Thus, the concentration of Zn in some vegetables and animals food products and other dietary food items has been increased. So far, the effects of long term Zn overload in the body have not been reviewed. Consumption of excess Zn in diet for longer period of time may contribute obesity and related diseases in adolescence, copper (Cu)-deficiency related abnormalities in the adults and pregnant women. Excess Zn in diet makes diabetic patients more vulnerable due to increase in glycosylated haemoglobin level in the blood. The various aspects about harmful effect of excess Zn in diet is given in this communication.